Nano Medical Hydroxyapatite Modern Technology and Particle Characteristics
The APAGARD PREMIO tooth paste utilizes medical-grade nano hydroxyapatite (nano-mHAP) as its key energetic component, containing crystalline calcium phosphate [Ca10(PO4)6(OH)2] bits manufactured at nanometer range with median size of 50-100 nanometers. This bit size makes it possible for penetration into enamel micropores and subsurface demineralized areas measuring 1-10 micrometers deepness, assisting in ionic bonding and crystal latticework integration with natural enamel framework consisting of around 96% hydroxyapatite by weight. The APAGARD Premio tooth paste 105g tube layout provides about 50-60 applications based on advised 1.5-2.0 gram dose per cleaning session, preserving regular nano-mHAP concentration throughout the product’s 36-month shelf life when kept at area temperature level (20-25 ° C). The APAGARD Premio toothpaste 3.7 oz volumetric spec represents conventional 105-gram weight, with paste thickness of around 1.4 g/mL audit for combination of liquid phase, humectants, and suspended mineral fragments.
Bit surface measures 200-300 m ²/ g, providing substantial reactive user interface for calcium and phosphate ion exchange with saliva and enamel substratum during normal 2-3 min cleaning duration. The APAGARD PREMIO dual mint tooth paste taste system utilizes menthol (0.3-0.5% by weight) and pepper mint oil (0.2-0.4%) for breath freshening while preserving pH stability between 6.5-7.5, critical for protecting against nano-mHAP bit aggregation listed below pH 6.0 or dissolution above pH 8.0. The APAGARD PREMIO fluoride free tooth paste formulation addresses customer segments avoiding fluoride because of oral fluorosis problems in kids or preference for biomimetic remineralization techniques, counting exclusively on nano-mHAP for enamel defense without fluoride’s conversion of hydroxyapatite to fluorapatite [Ca10(PO4)6F2]
Remineralization Systems and Professional Efficacy Specifications
The APAGARD PREMIO nano hydroxyapatite tooth paste runs via three-phase device: first fragment adsorption onto enamel surface area through electrostatic destination occurring within 30-60 secs of call, diffusion into subsurface sores over 1-2 minute cleaning period, and continual mineral ion launch during 4-6 hour post-application period as bits gradually liquify in acidic oral environment (pH 5.5-6.5). The APAGARD PREMIO nano mHAP tooth paste concentration of 10-12% by weight stands for premium solution tier compared to typical variations consisting of 7-9% nano-mHAP, making it possible for accelerated remineralization kinetics for moderate enamel demineralization situations. The APAGARD PREMIO enamel remineralization toothpaste achieves quantifiable enamel microhardness recovery within 14 days of twice-daily application, with Vickers indentation testing at 200-gram tons showing 15-25% hardness rise in artificially demineralized enamel over 28-day test periods.
Professional researches gauging surface area roughness by means of atomic pressure microscopy reveal the APAGARD PREMIO enamel repair tooth paste decreasing enamel Ra values from typical 0.8-1.2 micrometers in used enamel to 0.3-0.5 micrometers after 4 weeks of twice-daily usage. The APAGARD PREMIO natural bleaching toothpaste accomplishes optical lightening up via surface area smoothing instead of chemical lightening, as nano-mHAP bits fill microscopic surface area abnormalities that spread event light, boosting specular reflection coefficient from 15-25% (harsh enamel) to 40-55% (smooth enamel) without permeating enamel structure via oxidative procedures. Scanning electron microscopy imaging at 5,000-10,000 × zoom shows particle deposition loading enamel surface area problems, with energy-dispersive X-ray spectroscopy validating calcium-to-phosphate molar ratio of 1.65-1.67 matching stoichiometric hydroxyapatite structure.
Antimicrobial Characteristics and Biofilm Disturbance
The APAGARD PREMIO plaque elimination toothpaste antimicrobial activity stems from nano-mHAP’s adsorption of bacterial cells and healthy proteins onto bit surface, minimizing planktonic germs focus in saliva by 30-50% and inhibiting biofilm formation via affordable surface occupation on enamel pellicle layer. The APAGARD PREMIO discolor control toothpaste unpleasant system employs moisturized silica at 15-20% concentration with Family member Dentin Abrasivity (RDA) value of 90-110, giving enough mechanical activity for external tarnish elimination from chromogenic substances (coffee tannins, tea polyphenols, red wine anthocyanins) while continuing to be below 150 RDA limit related to excessive enamel wear over prolonged usage periods surpassing 5 years.
Taste Chemistry and Sensory Characteristics
The APAGARD PREMIO breath refreshing tooth paste unstable substance account consists of menthol, eucalyptol, and thymol at consolidated concentration of 0.5-0.8%, providing instant breath refreshing with volatile natural substance variation of malodorous sulfur substances (hydrogen sulfide, methyl mercaptan) created by anaerobic microbial metabolic process. The APAGARD PREMIO tooth cavity protection tooth paste optimal application protocol specifies 0.8-1.0 gram dose related to soft-bristle tooth brush with bristle diameter 0.15-0.20 mm, utilizing customized Bass technique with 45-degree bristle angle to gingival margin, circular movement covering 2-3 teeth per location, and 2-3 minute total brushing duration maintaining force listed below 150 grams to prevent enamel abrasion.
The APAGARD PREMIO mild tooth paste for households security account across age ranges originates from nano-mHAP’s biocompatibility, as ingested bits undertake dissolution in gastric acid (pH 1.5-3.5) releasing calcium and phosphate ions that the body processes via regular mineral homeostasis pathways without systemic poisoning concerns. The APAGARD PREMIO tooth paste for delicate teeth addresses dentin hypersensitivity with nano-mHAP fragment deposition within subjected dentin tubules determining 1-3 micrometers size, literally occluding tubule openings and decreasing hydraulic conductance by 60-80% within 2 week of twice-daily application as gauged by fluid flow studies. Those who acquire APAGARD PREMIO toothpaste get solution preserving nano-mHAP suspension stability with xanthan periodontal (0.5-1.0%) supplying thixotropic buildings that promote fragment resuspension with tube pressing action. Those that buy APAGARD PREMIO toothpaste 105g acquire about 50-60 applications making it possible for regular remineralization result throughout the 4-8 week duration needed for quantifiable enamel microhardness healing.
Daily Application Protocols and Long-Term Upkeep
The APAGARD PREMIO toothpaste for daily enamel treatment maintenance program calls for twice-daily application adhering to dishes when salivary pH goes down to 5.5-6.0 because of bacterial acid production from nutritional carb metabolic process, creating demineralization problems where enamel loses calcium and phosphate ions. The APAGARD PREMIO toothpaste with nano mHAP for enamel support bit concentration allows quantifiable surface microhardness recuperation as deposited particles slowly dissolve in acidic dental atmosphere offering sustained mineral ion release throughout neutral pH healing durations. The APAGARD PREMIO toothpaste for enamel fortifying device enhances enamel microhardness by 15-25% over 28-day application period with indentation depth decreasing from 80-100 micrometers in demineralized enamel to 60-75 micrometers in cured enamel as validated by lab testing protocols.
The APAGARD PREMIO toothpaste for smooth enamel really feel surface appearance modification lowers enamel roughness from 0.8-1.2 micrometers in used enamel to 0.3-0.5 micrometers after 4 weeks of twice-daily usage, approaching the 0.1-0.2 micrometer Ra values of intact enamel surface. The APAGARD PREMIO toothpaste for stain control and bleaching combines mechanical stain removal with moisturized silica unpleasant with optical lightening up from surface smoothing, removing microscale functions that scatter event light without modifying intrinsic tooth color through chemical whitening processes. The APAGARD PREMIO tooth paste for fresh breath and tidy teeth taste persistence expands 2-4 hours post-brushing with residual menthol and pepper mint oil components adhering to oral mucosa with steady release keeping fresh preference perception.
Formula Stability and Storage Space Demands
The APAGARD PREMIO toothpaste for plaque control rheological residential or commercial properties show shear-thinning habits with viscosity reducing from 100,000 cP at rest to 5,000-10,000 cP under brushing shear prices (100-1000 s ⁻¹), assisting in brush loading and interdental infiltration. The APAGARD PREMIO toothpaste for mild family brushing sodium lauryl sulfate content (1-2%) provides surfactant activity for particles removal while continuing to be listed below concentrations over 2.5% connected with dental mucosa irritation in delicate individuals or kids. The APAGARD PREMIO toothpaste for delicate teeth and enamel care dual-action approach addresses both hypersensitivity with tubule occlusion and enamel demineralization with mineral substitute, appropriate for individuals experiencing several concurrent conditions impacting 10-30% of adult populace.
The APAGARD PREMIO tooth paste with dual mint flavor utilizes menthol’s modest lipophilicity (log P = 3.4) enabling dividers right into dental mucosa lipid bilayers with progressive release extending flavor perseverance. The APAGARD PREMIO fluoride complimentary tooth paste for daily use chemical system utilizes salt benzoate (0.1-0.3%) maintaining microbiological stability with bacterial matter listed below 10 CFU/g over 36-month storage space duration meeting pharmaceutical-grade criteria. The APAGARD PREMIO nano hydroxyapatite toothpaste 105g tube packaging makes use of aluminum-plastic laminate construction preventing moisture loss and maintaining paste uniformity over product lifespan. Added technical requirements and application assistance are readily available at http://theapagard.com/ for individuals calling for in-depth details on nano-mHAP remineralization technology and optimum cleaning procedures.